Journal article

Doxorubicin loaded nanodiamond-silk spheres for fluorescence tracking and controlled drug release

A Khalid, AN Mitropoulos, B Marelli, S Tomljenovic-Hanic, FG Omenetto

Biomedical Optics Express | Published : 2015

Abstract

Nanoparticle (NP) based technologies have proved to be considerably beneficial for advances in biomedicine especially in the areas of disease detection, drug delivery and bioimaging. Over the last few decades, NPs have garnered interest for their exemplary impacts on the detection, treatment, and prevention of cancer. The full potential of these technologies are yet to be employed for clinical use. The ongoing research and development in this field demands single multifunctional composite materials that can be employed simultaneously for drug delivery and biomedical imaging. In this manuscript, a unique combination of silk fibroin (SF) and nanodiamonds (NDs) in the form of nanospheres are fa..

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Grants

Awarded by ARC Australian Research Fellowship


Funding Acknowledgements

The authors wish to acknowledge Dr. Richard de Boer, Royal Melbourne Hospital, for helpful discussions about this work. A. Khalid is supported by Melbourne Research Scholarships awarded by The University of Melbourne and acknowledges Melbourne Scholarships for providing ORES funding to visit Prof. F.G. Omenetto at Tufts University. S. Tomljenovic-Hanic is supported by an ARC Australian Research Fellowship (DP1096288). The numerical part of research was undertaken with the assistance of resources provided at the NCI National Facility systems at The Australian National University through the National Computational Merit Allocation Scheme supported by the Australian Government.